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Home NFT

This Founder Built Natural GLP-1 Alternative Before the Boom

Digital Pulse by Digital Pulse
February 11, 2026
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This Founder Built Natural GLP-1 Alternative Before the Boom
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Opinions expressed by Entrepreneur contributors are their very own.

Key Takeaways

Evolv co-founder Becca McCarthy noticed a large GLP-1 development — and constructed a pure different to match it.
She believes urge for food management doesn’t want a prescription, a needle, or a stigma.

Becca McCarthy says she’s all the time been good at recognizing when one thing is about to interrupt into the mainstream. She has spent her profession inside startups, serving to flip early curiosity into actual markets and constructing merchandise earlier than most individuals understand there’s demand for them.

That’s why, a number of years in the past, when she began listening to folks in her community speaking about GLP-1 medication, she paid consideration. GLP‑1 medication reminiscent of Ozempic and Zepbound are among the many quickest‑rising prescription medicines within the U.S., with whole GLP‑1 gross sales worldwide estimated at round $50 billion.

However McCarthy was listening to about them lengthy earlier than they grew to become cultural shorthand. Her in any other case wholesome family and friends have been injecting these medication for weight reduction and retaining it principally to themselves. Utilizing a medicine designed for diabetes to handle urge for food carried a stigma. It was thought of dishonest and ran counter to the wellness world’s insistence on clear consuming, self-discipline, and willpower.

That’s when she noticed a possibility hole. “I assumed, what in the event you might give you a remedy for this large demand that’s constructing for efficacy from GLP-1 receptor activation with out upsetting the eating regimen and train police, then you could have a large resolution.”

The reply ultimately grew to become Evolv, a pure, oral complement designed to imitate the results of GLP-1 with out needles, prescriptions, artificial hormones, or the judgment that surrounds prescription drugs.

Associated: This Is How GLP-1 Medicine Are Forcing Restaurant Chains to Change Their Menus

A pure resolution

To get there, McCarthy teamed up in 2023 with Dr. Corey Henderson, a molecular biologist who had designed a novel peptide that might work together with GLP1 and GIP receptors in the identical approach that the medication do, however in a completely pure approach with none synthetics. The corporate says the product helps urge for food regulation and metabolic perform by activating the identical pathways that make pharmaceutical GLP-1s so compelling—however by way of a pure mechanism that begins within the intestine.

They experimented with totally different supply strategies—first a shake, then a dietary complement—and ultimately landed on a tablet. As soon as they acquired encouraging suggestions from early knowledge, McCarthy dedicated totally. “I spotted that is going to vary the world. So I simply went all in,” she says.

Associated: How This Founder Turned ‘Dry January’ Right into a Yr-Spherical Motion — And Constructed America’s #1 Non-Alcoholic Beer Model

Overcoming hurdles

McCarthy has needed to push by way of her share of hurdles. One of the vital persistent is being taken critically as a feminine founder. “There may be an inherent bias that we’re up in opposition to, the place it’s very easy for me to be perceived as a extremely competent and investable founder or entrepreneur or boss or chief, however it’s very arduous for me to be perceived as likable in that function,” she says.

McCarthy remembers instances she’s gone to pitch conferences and was mistaken for an admin. One other time, she was turned down solely to observe males get funding with a far inferior concept. It’s arduous,” she says. “It’s not handed to you in the identical approach if you’re a feminine.”

One other problem has been the silence that comes with success. Clients see outcomes, however they don’t essentially wish to clarify how they acquired them. “Individuals need everyone to suppose it’s as a result of they went to so many Pilates lessons,” she says. It’s arduous to construct phrase of mouth when the very factor folks like most a few product is that nobody is aware of they’re utilizing it.

Regardless of the problem of getting prospects to speak brazenly concerning the product, McCarthy isn’t dwelling on the advertising dilemma. She’s centered on serving to folks handle their urge for food with out requiring a physician, a prescription, or a needle. It’s the outcomes that may finally make the most important distinction. “Individuals simply wish to look higher bare. So once we ship on that, that’s what works.”

Key Takeaways

Evolv co-founder Becca McCarthy noticed a large GLP-1 development — and constructed a pure different to match it.
She believes urge for food management doesn’t want a prescription, a needle, or a stigma.

Becca McCarthy says she’s all the time been good at recognizing when one thing is about to interrupt into the mainstream. She has spent her profession inside startups, serving to flip early curiosity into actual markets and constructing merchandise earlier than most individuals understand there’s demand for them.

That’s why, a number of years in the past, when she began listening to folks in her community speaking about GLP-1 medication, she paid consideration. GLP‑1 medication reminiscent of Ozempic and Zepbound are among the many quickest‑rising prescription medicines within the U.S., with whole GLP‑1 gross sales worldwide estimated at round $50 billion.



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